综合性认知康复训练在阿尔茨海默病患者中应用的效果评价(1)
[摘要] 目的 探討综合性认知康复训练在阿尔茨海默病(AD)患者中应用的效果评价。 方法 选取2015年1月～2017年12月老年科住院治疗的AD患者74例，随机分为康复组和常规组。两组均予以尼麦角林片10 mg/次，2次/d+吡垃西坦片2片/次，3次/d联合治疗。常规组给予宣传教育、心理安慰、用药干预、饮食和睡眠指导等常规干预措施。康复组在常规组基础上给予综合性认知康复训练。两组均干预12周。比较两组患者治疗前后认知功能及日常生活能力的变化，并比较其临床效果。 结果 干预12周后，两组ADAS-cog评分较干预前显著下降，MoCA评分及ADAS-ADL较干预前显著上升(P<0.05或P<0.01)，且康复组下降或上升值较常规组更显著(P<0.05);同时康复组临床总有效率(94.59%)较常规组(78.38%)更佳(χ2=4.163，P<0.05)。 结论 综合性认知康复训练用于AD患者的临床效果确切，不仅能更明显改善患者的认知功能，延缓认知功能障碍的进展，而且能提高患者的日常生活能力，增强其独立生活能力。
[关键词] 阿尔茨海默病;综合性认知康复训练;认知功能;日常生活能力
, http://www.100md.com
[中图分类号] R743.1 [文献标识码] B [文章编号] 1673-9701(2020)12-0098-04
[Abstract] Objective To explore the effect of comprehensive cognitive rehabilitation training in patients with Alzheimer's disease (AD). Methods 74 patients with AD who were hospitalized in the Deprtmetn of Geriatrics from January 2015 to December 2017 were randomly divided into rehabilitation group and routine group. The both groups were given Nigra horn tablets 10 mg/time， twice a day +piracetam 2 tablets/time， 3 times/d. The routine group gave routine interventions such as education， psychological comfort， medication intervention， diet and sleep guidance. The rehabilitation group was given comprehensive cognitive rehabilitation training on the basis of the treatment in the routine group. Both groups were treated for 12 weeks. The changes of cognitive function and daily living ability between two groups before and after treatment were observed and compared， and the clinical effects were compared. Results After 12 weeks of intervention， the ADAS-cog scores of the two groups were significantly lower than those before the intervention， and the MoCA score and ADAS-ADL were significantly higher than those before the intervention(P<0.05 or P<0.01). And the decrease or increase of the rehabilitation group was more significant than that of the conventional group(P<0.05). At the same time， the total clinical effective rate (94.59%) was better in the rehabilitation group than that (78.38%) in the conventional group (χ2=4.163， P<0.05). Conclusion The comprehensive cognitive rehabilitation training for patients with AD has a clear clinical effect， which not only can significantly improve the cognitive function of patients， delay the progress of cognitive dysfunction， but also can improve the daily living ability of patients and enhance their independent living ability. , 百拇医药(胡国娣 向梅 张学平)
[关键词] 阿尔茨海默病;综合性认知康复训练;认知功能;日常生活能力
, http://www.100md.com
[中图分类号] R743.1 [文献标识码] B [文章编号] 1673-9701(2020)12-0098-04
[Abstract] Objective To explore the effect of comprehensive cognitive rehabilitation training in patients with Alzheimer's disease (AD). Methods 74 patients with AD who were hospitalized in the Deprtmetn of Geriatrics from January 2015 to December 2017 were randomly divided into rehabilitation group and routine group. The both groups were given Nigra horn tablets 10 mg/time， twice a day +piracetam 2 tablets/time， 3 times/d. The routine group gave routine interventions such as education， psychological comfort， medication intervention， diet and sleep guidance. The rehabilitation group was given comprehensive cognitive rehabilitation training on the basis of the treatment in the routine group. Both groups were treated for 12 weeks. The changes of cognitive function and daily living ability between two groups before and after treatment were observed and compared， and the clinical effects were compared. Results After 12 weeks of intervention， the ADAS-cog scores of the two groups were significantly lower than those before the intervention， and the MoCA score and ADAS-ADL were significantly higher than those before the intervention(P<0.05 or P<0.01). And the decrease or increase of the rehabilitation group was more significant than that of the conventional group(P<0.05). At the same time， the total clinical effective rate (94.59%) was better in the rehabilitation group than that (78.38%) in the conventional group (χ2=4.163， P<0.05). Conclusion The comprehensive cognitive rehabilitation training for patients with AD has a clear clinical effect， which not only can significantly improve the cognitive function of patients， delay the progress of cognitive dysfunction， but also can improve the daily living ability of patients and enhance their independent living ability. , 百拇医药(胡国娣 向梅 张学平)
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